Sample of projects the Amber Biology consultants have worked on, both as part of the Amber Biology team and in their individual careers.
projects
When one of our clients really wants to understand how a particular biological pathway works, we can build it for them …
A machine learning algorithm was developed that could reconstruct ab initio, the low resolution structure of a protein from its x-ray diffraction intensities alone.
Amber Biology is very excited to have been hired as a contractor for NASA’s TESS (Transiting Exoplanet Survey Satellite) mission. Due to be launched from Cape Canaveral as early as March 2018, the TESS spacecraft will search for exoplanets orbiting distant stars…
Amber Biology has been engaged to perform a full-scale overhaul of Python for Population Genomics (PyPop). PyPop is an open-source framework for large-scale population genomics. implemented to probe genotype data for signatures of natural selection.…
Amber Biology was hired to create sophisticated, custom machine control and user interface software for a medical diagnostic robot being developed by a team at Harvard Medical School
Amber Biology created code to implement advanced pattern matching algorithms for a novel RNA-based disease diagnostic platform…
Algorithms were implemented in Python to correlate biomolecule manufacturing outcomes with process parameters, in order to improve the consistency and predictability of the manufacturing process…
A collaborative, cloud-based software platform being developed for modeling complex cell signaling pathways. This platform implemented a stochastic modeling approach underpinned by a rigorous semantic formalism that made possible a set of powerful static analyses of the modeled systems.
A joint bioinformatics and laboratory-based program for predicting and re-engineering immunogenic regions in biologics that would eventually become a part of the standard workflow for all new biologic development programs throughout a global pharmaceutical company…
Software development of Swarm, a pioneering open-source agent-based modeling toolkit from the Santa Fe Institute, and consulting with scientists using this toolkit to model complex biological systems such as transcription factor networks…
A commercial software-as-a-service (Saas) platform built on Amazon Web Services infrastructure, to allow biologists to collaboratively model and stimulate cell-signaling networks…
Hidden Markov Model algorithms for searching protein sequences for potential prion-like, structured regions of proteins were implemented in an Open Source software platform available to scientists under the MIT License…
Leader of product development for a cloud-based nucleotide design and manufacturing portal that handled the design, ordering, manufacturing and delivery of novel nucleotides…
An Amber principal was involved in the development of the open-source COSMOS Python library for managing large-scale sequencing workflows.
Book
A gentle introduction to computer programming in Python specifically for biologists with no prior experience of writing code. Visit book website.
Amber Biology has completed multiple projects involving the design and engineering of biomolecules, including therapeutic proteins and oligonucleotides, and RNA biomarkers for disease diagnosis…