A potential route to antiviral therapy for coronavirus.

Deeper knowledge of the mechanisms of coronavirus replication and assembly has been obtained from structural biology.

Biomarkers, ImmunotherapyGordon WebsterMarch 22, 2020covid19, sars_cov_2, sarscov2, structuralbiology, xraycrystallography, proteins, proteaseinhibitors, antiviral, bioinformatics, drugdevelopment, pandemic, coronavirus

Bayes Theorem applied to biomarker design

Here we develop a simple Python function to help us evaluate the performance of biomarkers in diagnosing disease.

Computational Biology, Mathematical Biology, Python, Bioinformatics, Statistical Analysis, BiomarkersGordon WebsterApril 20, 2018

If you really want to understand how a biological pathway works, build one

Amber Biology was recently commissioned by a biotechnology company, to build a dynamic, agent-based model of a biological pathway.

An Intuitive Video Introduction To Bayes’ Theorem

A little while back on The Digital Biologist, we published a 2-part introduction to Bayes’ Theorem ...

Bioinformatics, Biomarkers, Computational Biology, Mathematical Biology, Statistical Analysis, TrainingGordon WebsterJuly 25, 2016bayes theorem, statistics, statistical analysis, biostatistics, biomarkers, probability, conditional probability, bayesian

Biomarker Design: Lessons from Bayes' Theorem

Actionable insights that can be gained by the application of Bayesian analysis to the design of biomarkers ...

Bioinformatics, Biomarkers, Computational Biology, Mathematical Biology, Statistical AnalysisGordon WebsterAugust 14, 2015

A theorem for all seasons

Why is Bayes’ Theorem so useful and what does it have to teach us as life scientists?

Biomarkers, Computational Biology, Mathematical Biology, Statistical AnalysisGordon WebsterAugust 14, 2015bayes theorem, statistics, statistical analysis, biostatistics, biomarkers, probability, conditional probability, bayesian

Biological models: Much more than just a weather forecast

Biological modeling is not yet in the mainstream of biological research in the way that it is in other scientific and technical areas like physics and engineering ...

Biomarkers, Cell Signaling, Computational Biology, Mathematical Biology, Modeling & Simulation, Systems Biology, AlgorithmsGordon WebsterAugust 14, 2015computational biology, systems biology, bioinformatics, modeling, simulation, stochastic modeling, dynamic modeling, deterministic modeling, calculus, differential equations

Biologists Flirt With Models

Early developments in biological modeling hold the potential to forge a knowledge revolution in biology and to bring modeling into the mainstream of biological research …

Algorithms, Biomarkers, Cell Signaling, Computational Biology, Mathematical Biology, Modeling & Simulation, Systems BiologyGordon WebsterAugust 14, 2015computational biology, systems biology, bioinformatics, modeling, simulation, stochastic modeling, dynamic modeling, deterministic modeling, calculus, differential equations, complex adaptive systems